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Anatomy of a homeoprotein revealed by the analysis of human MODY3 mutations

An unusual HIV type 1 env sequence embedded in a mosaic virus from Cameroon: identification of a new env clade. European Network on the study of in utero transmission of HIV-1

© Research

Publication : FEMS immunology and medical microbiology

Molecular epidemiology of quinolone resistance and comparative in vitro activities of new quinolones against European Staphylococcus aureus isolates

Team: Microbial Evolutionary Genomics

Member: Sylvain Brisse

Scientific Fields

Diseases

Organisms

Applications

Technique

Published in FEMS immunology and medical microbiology - 01 Dec 1999

Schmitz FJ, Fluit AC, Brisse S, Verhoef J, Köhrer K, Milatovic D

Link to Pubmed [PMID] – 10575140

FEMS Immunol. Med. Microbiol. 1999 Dec;26(3-4):281-7

New fluoroquinolones (FQ) may possibly be used as alternative therapeutic options for Staphylococcus aureus infections. Our objectives were: (1) to define the in vitro activities of seven FQs in a collection of 434 methicillin-susceptible and 457 methicillin-resistant S. aureus from 23 European university hospitals; (2) to characterise the prevalence of mutations in the grlA and gyrA genes in all ciprofloxacin-resistant (n=433) isolates of S. aureus; (3) to determine the percentage of ciprofloxacin-resistant S. aureus strains with measurable quinolone efflux.

Published on: 01 Dec 1999