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© A. Alanio, E. Perret
Prolifération de Cryptococcus neoformans dans des macrophages murins.
Publication : Mycopathologia

Microsporum praecox: molecular identification of a new case and review of the literature.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Mycopathologia - 25 Jul 2010

Alanio A, Romand S, Penso-Assathiany D, Foulet F, Botterel F,

Link to Pubmed [PMID] – 20658321

Link to DOI [DOI] – 10.1007/s11046-010-9348-8

Mycopathologia 2011 Jan; 171(1): 61-5

We report a rare case of dermatophytosis due to Microsporum praecox in a 28-year-old female horse rider. The skin lesion was located on the right external malleolus. Microscopic examination of skin scrapings revealed a dermatophyte which was also isolated in culture. The identification of M. praecox was confirmed by molecular biology (sequence analysis of PCR products amplified from internal transcribed spacer regions with universal primers). Combined antifungal therapy with oral terbinafine and topical cyclopiroxolamide resulted in complete remission of the fungal lesion within 1 month. Since 1944, only 29 cases of human M. praecox infection have been reported in the literature. The clinical features and treatment of these cases are reviewed. The prevalence of M. praecox infection is probably underestimated, and systematic molecular identification could improve our understanding of the epidemiology of this fungal dermatosis.

https://pubmed.ncbi.nlm.nih.gov/20658321