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© Research
Publication : The Journal of infectious diseases

Micro-hotspots of Risk in Urban Cholera Epidemics

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The Journal of infectious diseases - 11 May 2018

Azman AS, Luquero FJ, Salje H, Naibei Mbaïbardoum N, Adalbert N, Ali M, Bertuzzo E, Finger F, Toure B, Massing LA, Ramazani R, Saga B, Allan M, Olson D, Leglise J, Porten K, Lessler J

Link to Pubmed [PMID] – 29757428

J. Infect. Dis. 2018 May;

Targeted interventions have been delivered to neighbors of cholera cases in major epidemic responses globally despite limited evidence for the impact of such targeting. Using data from urban epidemics in Chad and D.R. Congo we estimate the extent of spatiotemporal zones of increased cholera risk around cases. In both cities, we found zones of increased risk of at least 200-meters during the 5-days immediately following case presentation to a clinic. Risk was highest for those living closest to cases and diminished in time and space similarly across settings. These results provide a rational basis for rapidly delivering targeting interventions.

https://www.ncbi.nlm.nih.gov/pubmed/29757428