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© Thierry Blisnick & Philippe Bastin, Institut Pasteur
Bloodstream Trypanosoma brucei cell
Publication : Cellular microbiology

Intravital imaging of host-parasite interactions in organs of the thoracic and abdominopelvic cavities.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cellular microbiology - 01 Jun 2020

De Niz M, Carvalho T, Penha-Gonçalves C, Agop-Nersesian C,

Link to Pubmed [PMID] – 32149435

Link to DOI – 10.1111/cmi.13201

Cell Microbiol 2020 06; 22(6): e13201

Infections with protozoan and helminthic parasites affect multiple organs in the mammalian host. Imaging pathogens in their natural environment takes a more holistic view on biomedical aspects of parasitic infections. Here, we focus on selected organs of the thoracic and abdominopelvic cavities most commonly affected by parasites. Parasitic infections of these organs are often associated with severe medical complications or have health implications beyond the infected individual. Intravital imaging has provided a more dynamic picture of the host-parasite interplay and contributed not only to our understanding of the various disease pathologies, but has also provided fundamental insight into the biology of the parasites.