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© Fabrice Chrétien with Ultrapole, colorized by Jean-Marc Panaud
Cellule souche (en jaune) de muscle squelettique partiellement recouverte par la membrane basale, migrant sur une fibre musculaire (en bleu).
Publication : Veterinary pathology

Internet and print resources to facilitate pathology analysis when phenotyping genetically engineered rodents

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Veterinary pathology - 08 Aug 2011

Bolon B, Couto S, Fiette L, Perle KL

Link to Pubmed [PMID] – 21825311

Vet. Pathol. 2012 Jan;49(1):224-35

Genetically engineered mice and rats are increasingly used as models for exploring disease progression and mechanisms. The full spectrum of anatomic, biochemical, and functional changes that develop in novel, genetically engineered mouse and rat lines must be cataloged before predictions regarding the significance of the mutation may be extrapolated to diseases in other vertebrate species, including humans. A growing list of reference materials, including books, journal articles, and websites, has been produced in the last 2 decades to assist researchers in phenotyping newly engineered rodent lines. This compilation provides an extensive register of materials related to the pathology component of rodent phenotypic analysis. In this article, the authors annotate the resources they use most often, to allow for quick determination of their relevance to research projects.

http://www.ncbi.nlm.nih.gov/pubmed/21825311