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© Research
Publication : Beilstein journal of organic chemistry

Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Beilstein journal of organic chemistry - 04 Sep 2013

Coutant E, Young PC, Barker G, Lee AL

Link to Pubmed [PMID] – 24062845

Beilstein J Org Chem 2013;9:1797-806

A gold(I)-catalysed reaction of allylic alcohols and phenols produces chromans regioselectively via a one-pot Friedel-Crafts allylation/intramolecular hydroalkoxylation sequence. The reaction is mild, practical and tolerant of a wide variety of substituents on the phenol.

http://www.ncbi.nlm.nih.gov/pubmed/24062845