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© Research
Publication : Nature reviews. Microbiology

Going local: technologies for exploring bacterial microenvironments

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Nature reviews. Microbiology - 01 May 2013

Wessel AK, Hmelo L, Parsek MR, Whiteley M

Link to Pubmed [PMID] – 23588251

Nat. Rev. Microbiol. 2013 May;11(5):337-48

Microorganisms lead social lives and use coordinated chemical and physical interactions to establish complex communities. Mechanistic insights into these interactions have revealed that there are remarkably intricate systems for coordinating microbial behaviour, but little is known about how these interactions proceed in the spatially organized communities that are found in nature. This Review describes the technologies available for spatially organizing small microbial communities and the analytical methods for characterizing the chemical environment surrounding these communities. Together, these complementary technologies have provided novel insights into the impact of spatial organization on both microbial behaviour and the development of phenotypic heterogeneity within microbial communities.

https://www.ncbi.nlm.nih.gov/pubmed/23588251