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© A. Alanio, E. Perret
Prolifération de Cryptococcus neoformans dans des macrophages murins.
Publication : Journal de mycologie médicale

Eumycetoma of the foot caused by Exophiala jeanselmei in a Guinean woman

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal de mycologie médicale - 17 Jul 2013

Desoubeaux G, Millon A, Freychet B, de Muret A, Garcia-Hermoso D, Bailly E, Rosset P, Chandenier J, Bernard L

Link to Pubmed [PMID] – 23871385

J Mycol Med 2013 Sep;23(3):168-75

Eumycetomas are chronic infectious entities characterized by presence of mycotic grains in (sub-)cutaneous tissues, after accidental inoculation of an exogenous filamentous fungus in the skin. The lesions evolve towards painless pseudotumor of the soft parts. We report the original case of a Guinean woman exhibiting eumycetoma of the right foot. Both laboratory tests identified a dematiaceous fungus, Exophiala jeanselmei, as the responsible infectious agent. A medical treatment with voriconazole alone was sufficient to notice a substantial clinical improvement. This finding is unusual as E. jeanselmei is uncommon in Guinea-Conakry, and as optimal treatment rather associate antifungal azoles and surgical excision.

http://www.ncbi.nlm.nih.gov/pubmed/23871385