EUCAST technical note on Candida and micafungin, anidulafungin and fluconazole | Research - Institut Pasteur

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Published in Mycoses - 13 Jan 2014

Arendrup MC, Cuenca-Estrella M, Lass-Flörl C, Hope WW,

Link to Pubmed [PMID] – 24417759

Mycoses 2014 Jun;57(6):377-9

The European Committee on Antimicrobial Susceptibility Testing Subcommittee on Antifungal Susceptibility Testing has determined breakpoints for micafungin and revised breakpoints for anidulafungin and fluconazole for Candida spp. This Technical Note is based on the corresponding rationale documents (http://www.eucast.org). The micafungin breakpoints are based on PK data, animal PK/PD data, microbiological data and clinical experience. The anidulafungin breakpoints for C. parapsilosis and fluconazole breakpoints for C. glabrata have been modified to species-specific values that categorise the wild-type as intermediate to accommodate use of these compounds in some clinical situations.

Published on: 13 Jan 2014