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© Research
Publication : European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

Epidemiological typing of Bordetella pertussis isolates: recommendations for a standard methodology

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 01 Mar 2000

Mooi FR, Hallander H, Wirsing von König CH, Hoet B, Guiso N

Link to Pubmed [PMID] – 10795589

Eur. J. Clin. Microbiol. Infect. Dis. 2000 Mar;19(3):174-81

Pertussis is re-emerging in vaccinated populations, and to gain insight into the reasons for this development population-based studies are necessary. Unfortunately, various techniques are used to study Bordetella pertussis populations, hampering comparison between studies. A standard methodology for epidemiological typing of Bordetella pertussis isolates is proposed which is based on serotyping, pulsed-field gel electrophoresis and gene typing. Such a standard approach will allow comparisons between studies performed in different laboratories. Comparisons may reveal whether the epidemiological differences observed between countries are due for instance to different Bordetella pertussis populations or different vaccines used.

http://www.ncbi.nlm.nih.gov/pubmed/10795589