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A possible initial folding intermediate: the C-terminal proteolytic domain of tryptophan synthase beta chains folds in less than 4 milliseconds into a condensed state with non-native-like secondary structure

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

© Research

Publication : Gastroenterology

Enterocytozoon bieneusi infection in acquired immunodeficiency syndrome-related sclerosing cholangitis

Team: Archived: Immunobiology of Dendritic Cells

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Published in Gastroenterology - 01 May 1992

Pol S, Romana C, Richard S, Carnot F, Dumont JL, Bouche H, Pialoux G, Stern M, Pays JF, Berthelot P

Link to Pubmed [PMID] – 1568589

Gastroenterology 1992 May;102(5):1778-81

Acalculous cholecystitis and sclerosing cholangitis due to Cryptosporidium sp, and cytomegalovirus have been described in patients with the acquired immunodeficiency syndrome (AIDS). However, in about 40% of cases of AIDS-related biliary disease, no opportunistic pathogen is identified. The current case report describes the first case, to the best of the authors’ knowledge, of AIDS-related sclerosing cholangitis associated with microsporidiosis. Enterocytozoon bieneusi was detected in the duodenum and bile by means of light microscopy and confirmed by electron microscopy. Microsporidian infection should be suspected in patients with AIDS-related sclerosing cholangitis as well as in cases of diarrhea in which none of the usual pathogens are found.

Published on: 01 May 1992