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© A. Alanio, E. Perret
Prolifération de Cryptococcus neoformans dans des macrophages murins.
Publication : The Journal of infectious diseases

Dynamics of Pneumocystis carinii air shedding during experimental pneumocystosis

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The Journal of infectious diseases - 03 Mar 2011

Choukri F, Aliouat el M, Menotti J, Totet A, Gantois N, Garin YJ, Bergeron V, Dei-Cas E, Derouin F

Link to Pubmed [PMID] – 21372312

J. Infect. Dis. 2011 May;203(9):1333-6

To better understand the diffusion of Pneumocystis in the environment, airborne shedding of Pneumocystis carinii in the surrounding air of experimentally infected rats was quantified by means of a real-time polymerase chain reaction assay, in parallel with the kinetics of P. carinii loads in their lungs. P. carinii DNA was detected in the air 1 week after infection and increased until 4-5 weeks after infection before stabilizing. A significant correlation was shown between lung burdens and the corresponding airborne levels, suggesting the possibility of estimating the fungal lung involvement through quantification of Pneumocystis in the exhaled air.

http://www.ncbi.nlm.nih.gov/pubmed/21372312