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© Pierre Lafaye
Astrocytes marqués par des anticorps VHH anti-GFAP. Des anticorps d'alpagas dirigés contre une protéine spécifique des astrocytes, la GFAP (Glial Fibrillary Acidic Protein), ont été obtenus à partir de camélidés immunisés. La partie VHH (partie de l'anticorps qui reconnaît l'antigène) a été exprimée sous forme recombinante chez Escherichia coli.
Publication : PloS one

Dipstick for rapid diagnosis of Shigella flexneri 2a in stool

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in PloS one - 18 Apr 2007

Nato F, Phalipon A, Nguyen TL, Diep TT, Sansonetti P, Germani Y

Link to Pubmed [PMID] – 17440606

PLoS ONE 2007;2(4):e361

Shigellosis or bacillary dysentery, an acute bloody diarrhoea, is a major public health burden in developing countries. In the absence of prompt and appropriate treatment, the infection is often fatal, particularly in young malnourished children. Here, we describe a new diagnostic test for rapid detection, in stool, at the bedside of patients, of Shigella flexneri 2a, the most predominant agent of the endemic form of the disease.