Link to Pubmed [PMID] – 26447576
Link to DOI – 10.1016/j.neuron.2015.09.041S0896-6273(15)00830-2
Neuron 2015 Oct; 88(1): 110-26
Low-level perception results from neural-based computations, which build a multimodal skeleton of unconscious or self-generated inferences on our environment. This review identifies bottleneck issues concerning the role of early primary sensory cortical areas, mostly in rodent and higher mammals (cats and non-human primates), where perception substrates can be searched at multiple scales of neural integration. We discuss the limitation of purely bottom-up approaches for providing realistic models of early sensory processing and the need for identification of fast adaptive processes, operating within the time of a percept. Future progresses will depend on the careful use of comparative neuroscience (guiding the choices of experimental models and species adapted to the questions under study), on the definition of agreed-upon benchmarks for sensory stimulation, on the simultaneous acquisition of neural data at multiple spatio-temporal scales, and on the in vivo identification of key generic integration and plasticity algorithms validated experimentally and in simulations.