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© Research
Publication : Cell host & microbe

Compensating P. falciparum artemisinin resistance.

Member: Didier Ménard
Member: Lucien Platon
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cell host & microbe - 08 Dec 2021

Platon L, Cao J, Ménard D,

Link to Pubmed [PMID] – 34883062

Link to DOI – S1931-3128(21)00513-810.1016/j.chom.2021.11.007

Cell Host Microbe 2021 12; 29(12): 1732-1734

Amino acid deprivation from reduced hemoglobin degradation in Pfkelch13 artemisinin-resistant parasites reduces fitness. In this issue of Cell Host & Microbe, Mesén-Ramírez et al. decipher the role of nutrient permeable channel activity within the parasitophorous vacuolar membrane to compensate for this fitness cost in asexual blood-stage Plasmodium falciparum parasites.