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© Research
Publication : Science (New York, N.Y.)

Comment on “Seroevidence for H5N1 influenza infections in humans: meta-analysis”

Team: Epidemiology of Emerging Diseases
Member:
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Science (New York, N.Y.) - 22 Jun 2012

Van Kerkhove MD, Riley S, Lipsitch M, Guan Y, Monto AS, Webster RG, Zambon M, Nicoll A, Peiris JS, Ferguson NM

Link to Pubmed [PMID] – 22723396

Science 2012 Jun;336(6088):1506; author reply 1506

A better understanding of the severity of H5N1 in humans is needed. Wang et al. (Brevia, 23 March 2012, p. 1463; published online 23 February 2012) overinterpret the results of seroprevalence studies and take too little account of underlying uncertainties. Although the true risk of death from H5N1 infection will likely be lower than the 60% of reported laboratory-confirmed cases, there is little evidence of millions of missed infections.