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© Biologie structurale et chimie
Structure du domaine en doigt de zinc de la protéine NEMO, déterminée par Résonance magnétique nucléaire (RMN). Cette protéine jouant un rôle dans des maladies (cancer, inflammation), les connaissances acquises sur sa structure offrent de précieuses informations sur sa fonction.
Publication : Cold Spring Harbor protocols

Characterizing Mosquito Biting Behavior Using the BiteOscope.

Team: Chemogenomic and Biological Screening Platform (PF-CCB)
Member: Emilie Giraud
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cold Spring Harbor protocols - 05 Jul 2023

Murray GPD, Giraud E, Hol FJH

Link to Pubmed [PMID] – 36882291

Link to DOI – 10.1101/pdb.prot108176

Cold Spring Harb Protoc 2023 Jul; 2023(7): .pdb.prot108176

The biteOscope enables the high-resolution monitoring and video recording of blood-feeding mosquitoes. Mosquito biting is induced by combining host cues, an artificial bloodmeal, a membrane, and a transparent heater in a transparent behavioral arena. Machine vision techniques enable the tracking and pose estimation of individual mosquitoes to discern behavior and resolve individual feeding events. The workflow allows multiple replicates and large amounts of imaging data to be generated rapidly. These data are suitable for downstream analysis using machine learning tools for behavioral analysis, allowing subtle behavioral effects to be characterized.