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© Research
Publication : One health (Amsterdam, Netherlands)

Broad range molecular detection methods identify only Borrelia spp. in erythema migrans biopsies and blood of tick-bitten patients.

Team: Pathogen discovery
Team: Epidemiology of Emerging Diseases
Team: Clinical Investigation Platform ICAReB-Clin
Member: Philippe Pérot
Member: Laura Tondeur
Member: Delphine Chretien
Member: Nicole Corre-Catelin
Member: Marc Eloit
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in One health (Amsterdam, Netherlands) - 01 Dec 2024

Pérot P, Tondeur L, Moutailler S, Chrétien D, Corre-Catelin N, Vayssier-Taussat M, Eloit M, Chirouze C, Cazorla C

Link to Pubmed [PMID] – 39287136

Link to DOI – 10.1016/j.onehlt.2024.100886

One Health 2024 Dec; 19(): 100886

In this multicenter study conducted in France, we challenged the hypothesis of the transmission of pathogens other than Borrelia spp. in 22 patients developing erythema migrans following a tick bite. Using a combination of high-throughput microfluidic PCRs and agnostic metagenomics on skin biopsies and blood samples, no microorganisms other than Borrelia spp. was found.