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© Fabrice Chrétien with Ultrapole, colorized by Jean-Marc Panaud
Cellule souche (en jaune) de muscle squelettique partiellement recouverte par la membrane basale, migrant sur une fibre musculaire (en bleu).
Publication : Survey of ophthalmology

Blindness, weakness, and tingling

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Survey of ophthalmology - 06 Mar 2012

Biotti D, Vignal C, Sharshar T, Gout O, McCoy AN, Miller NR

Link to Pubmed [PMID] – 22398335

Surv Ophthalmol 2012 Nov;57(6):565-72

A previously healthy 50-year-old man complained of acute bilateral loss of vision over 24 hours associated with tingling of his hands and feet. During the first 48 hours of hospitalization, he evolved quadriplegia, facial diplegia, bulbar palsy, and respiratory distress requiring ventilator assistance. At the same time vision deteriorated to hand motions. Lumbar puncture, electromyography, and clinical findings were all consistent with Guillain-Barré syndrome. The diagnosis of concomitant bilateral optic neuritis was made. Tests for immunological, inflammatory, infectious, or genetic diseases were unremarkable. Within weeks, repeated treatments with intravenous immunoglobulin, plasmapheresis, and high-dose parenteral corticosteroids led to resolution of motor findings, although visual acuity improved only to 20/100 OD and count fingers at 6 feet OS. Guillain-Barré syndrome-associated optic neuritis is rare and may be associated with an underlying Mycoplasma pneumoniae infection.

http://www.ncbi.nlm.nih.gov/pubmed/22398335