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© Artur Scherf
Scanning Electron Microscopy of Red Blood Cell infected by Plasmodium falciparum.
Publication : Parasitology today (Personal ed.)

Biology of giant proteins of Plasmodium: resolution on polyacrylamide-agarose composite gels

Team: Biology of Host-parasite Interactions
Member: Denise Mattei
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Parasitology today (Personal ed.) - 01 Jan 1998

Wiesner J, Mattei D, Scherf A, Lanzer M

Link to Pubmed [PMID] – 17040689

Parasitol. Today (Regul. Ed.) 1998 Jan;14(1):38-40

The malaria parasite Plasmodium falciparum that infects humans encodes several extremely large proteins with molecular masses in the hundreds of thousands to megadalton range. Studies on the structure, function and antigenicity of these ;giant proteins’ are hindered by the inability to resolve them effectively in conventional polyacrylamide gels. In this report, Jochen Wiesner, Denise Mattei, Artur Scherf and Michael Lanzer describe a convenient gel system, based on a composite polyacrylamide-agarose matrix, which facilitates analysis of giant proteins.