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Identification of parasite co-factors that are critical for adhesion of P. falciparum–infected RBC
Artur Scherf (PI)
Although PfEMP1/var is studied in many laboratories in the world, a number of key questions remain unknown. By analysing a mutant parasite (D10) with a chromosome 9 deletion and loss of adhesion, we linked […]
2015Discovery of a novel and conserved Plasmodium falciparum exported protein that is important for adhesion of PfEMP1 at the surface of infected erythrocytes, Cell. Microbiol. 2015 Aug;17(8):1205-16.
2011Clag9 is not essential for PfEMP1 surface expression in non-cytoadherent Plasmodium falciparum parasites with a chromosome 9 deletion, PLoS ONE 2011;6(12):e29039.
2010Dual stage synthesis and crucial role of cytoadherence-linked asexual gene 9 in the surface expression of malaria parasite var proteins, Proc. Natl. Acad. Sci. U.S.A. 2010 Sep;107(38):16643-8.
2008Identification of a novel post-translational modification in Plasmodium falciparum: protein sumoylation in different cellular compartments, Cell. Microbiol. 2008 Oct;10(10):1999-2011.
2007Leishmania DNA is rapidly degraded following parasite death: an analysis by microscopy and real-time PCR, Microbes Infect. 2007 Sep;9(11):1307-15.
2005Transcriptome analysis of antigenic variation in Plasmodium falciparum–var silencing is not dependent on antisense RNA, Genome Biol. 2005;6(11):R93.
2005Apical expression of three RhopH1/Clag proteins as components of the Plasmodium falciparum RhopH complex, Mol. Biochem. Parasitol. 2005 Sep;143(1):20-8.
2004The Plasmodium falciparum clag9 gene encodes a rhoptry protein that is transferred to the host erythrocyte upon invasion, Mol. Microbiol. 2004 Apr;52(1):107-18.
2004Plasmodium falciparum glycogen synthase kinase-3: molecular model, expression, intracellular localisation and selective inhibitors, Biochim. Biophys. Acta 2004 Mar;1697(1-2):181-96.
2003Recombinant Duffy binding-like-alpha domains of Plasmodium falciparum erythrocyte membrane protein 1 elicit antibodies in rats that recognise conserved epitopes, Parasitol. Res. 2003 Aug;90(6):467-72.
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