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© Valérie Zeitoun
Stéthoscope. Centre Médical de l'Institut Pasteur (CMIP).
Publication : Journal of the American Academy of Dermatology

Bacteriology of hidradenitis suppurativa/acne inversa: A review

Team: Medical Center of the Institut Pasteur
Member: Aude Nassif
Member: Paul-Henri Consigny
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of the American Academy of Dermatology - 01 Nov 2015

Nikolakis G, Join-Lambert O, Karagiannidis I, Guet-Revillet H, Zouboulis CC, Nassif A

Link to Pubmed [PMID] – 26470608

J. Am. Acad. Dermatol. 2015 Nov;73(5 Suppl 1):S12-8

Given that follicular papules and pustules, as well as nodules and abscesses, are the clinical hallmarks of hidradenitis suppurativa (HS), an infectious, bacterial pathway has been suspected in the pathogenesis of this chronic, inflammatory condition. Elucidating the behavior and role of bacterial species in HS and their interaction with cutaneous innate immunity will provide more insight into the pathophysiology of this condition. This review of prospective investigations suggests a synergistic relationship between impaired innate immunity and microbial factors in the etiology of HS.