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© Research
Publication : Science (New York, N.Y.)

Assessing the global threat from Zika virus

Team: Mathematical Modelling Of Infectious Diseases
Member: Henrik Salje
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Science (New York, N.Y.) - 14 Jul 2016

Lessler J, Chaisson LH, Kucirka LM, Bi Q, Grantz K, Salje H, Carcelen AC, Ott CT, Sheffield JS, Ferguson NM, Cummings DA, Metcalf CJ, Rodriguez-Barraquer I

Link to Pubmed [PMID] – 27417495

Science 2016 Aug;353(6300):aaf8160

First discovered in 1947, Zika virus (ZIKV) infection remained a little-known tropical disease until 2015, when its apparent association with a considerable increase in the incidence of microcephaly in Brazil raised alarms worldwide. There is limited information on the key factors that determine the extent of the global threat from ZIKV infection and resulting complications. Here, we review what is known about the epidemiology, natural history, and public health effects of ZIKV infection, the empirical basis for this knowledge, and the critical knowledge gaps that need to be filled.