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Publication : Mammalian genome : official journal of the International Mammalian Genome Society

Analysis of major repetitive DNA sequences in the dog (Canis familiaris) genome

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Mammalian genome : official journal of the International Mammalian Genome Society - 01 Jul 1999

Bentolila S, Bach JM, Kessler JL, Bordelais I, Cruaud C, Weissenbach J, Panthier JJ

Link to Pubmed [PMID] – 10384043

Mamm. Genome 1999 Jul;10(7):699-705

A systematic screening and analysis of repeated DNA sequences from a dog genomic library composed of small DNA inserts enabled us to characterize abundant canine repetitive DNA families. Four main families were identified: i) a group of highly repeated tRNA-derived short interspersed repetitive DNA elements (tRNA-SINEs); ii) another type of SINE-like element that was mainly found inserted into long interspersed repetitive elements (LINEs); iii) LINEs of the L1 type; and iv) satellite or satellite-like DNA. Surprisingly, no SINEs derived from 7SL RNA were found in the dog genome. These data should help in the analysis of canine DNA sequences and in the design of canine genome mapping reagents.