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© Research
Publication : Journal of virology

Analysis of clinical ostreid herpesvirus 1 (Malacoherpesviridae) specimens by sequencing amplified fragments from three virus genome areas

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of virology - 14 Mar 2012

Renault T, Moreau P, Faury N, Pepin JF, Segarra A, Webb S

Link to Pubmed [PMID] – 22419803

J. Virol. 2012 May;86(10):5942-7

Although there are a number of ostreid herpesvirus 1 (OsHV-1) variants, it is expected that the true diversity of this virus will be known only after the analysis of significantly more data. To this end, we analyzed 72 OsHV-1 “specimens” collected mainly in France over an 18-year period, from 1993 to 2010. Additional samples were also collected in Ireland, the United States, China, Japan, and New Zealand. Three virus genome regions (open reading frame 4 [ORF4], ORF35, -36, -37, and -38, and ORF42 and -43) were selected for PCR analysis and sequencing. Although ORF4 appeared to be the most polymorphic genome area, distinguishing several genogroups, ORF35, -36, -37, and -38 and ORF42 and -43 also showed variations useful in grouping subpopulations of this virus.

http://www.ncbi.nlm.nih.gov/pubmed/22419803