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© A-M. Pais-Correia, M-I. Thoulouze, A. Alcover, A. Gessain
Mise en évidence de structures de type "biofilm ", formées par le rétrovirus HTLV-1 générés par des cellules infectées (cellules du haut), qui ont été transmis à un autre lymphocyte (cellule du bas). Micrographie en microscopie électronique à balayage. Image colorisée.
Publication : Open forum infectious diseases

Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Open forum infectious diseases - 06 Mar 2015

Sibon D, Cassar O, Duga I, Brouzes C, Ghez D, Pasquier C, Sibon C, Desrames A, Mortreux F, Wattel E, Bazarbachi A, Gessain A, Hermine O

Link to Pubmed [PMID] – 26380333

Open Forum Infect Dis 2015 Apr;2(2):ofv032

Adult T-cell leukemia/lymphoma (ATLL), a T-cell neoplasm caused by human T-cell lymphotropic virus type 1 (HTLV-1), develops in the majority of cases in individuals who were infected with HTLV-1 as young children, by their mother during prolonged breastfeeding. We report the case of a Caucasian French man, whose parents were HTLV-1-seronegative and who developed ATLL after HTLV-1 sexual transmission by a Cameroonian woman. This hypothesis was corroborated by genotyping of the patient’s virus, which revealed an HTLV-1B strain, found only in Central Africa, especially in Cameroon. Thus, ATLL may develop after HTLV-1 infection during adulthood, outside breastfeeding.

https://www.ncbi.nlm.nih.gov/pubmed/26380333