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© Research
Publication : Biophysical journal

A Primer on the Bayesian Approach to High-Density Single-Molecule Trajectories Analysis

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Biophysical journal - 29 Mar 2016

El Beheiry M, Türkcan S, Richly MU, Triller A, Alexandrou A, Dahan M, Masson JB

Link to Pubmed [PMID] – 27028631

Biophys. J. 2016 Mar;110(6):1209-15

Tracking single molecules in living cells provides invaluable information on their environment and on the interactions that underlie their motion. New experimental techniques now permit the recording of large amounts of individual trajectories, enabling the implementation of advanced statistical tools for data analysis. In this primer, we present a Bayesian approach toward treating these data, and we discuss how it can be fruitfully employed to infer physical and biochemical parameters from single-molecule trajectories.

https://www.ncbi.nlm.nih.gov/pubmed/27028631