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© Xavier Montagutelli, Institut Pasteur
Publication : Genome research

A high-resolution microsatellite map of the mouse genome.

Team: Mouse Genetics
Member: Xavier Montagutelli
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Genome research - 01 May 1998

Rhodes M, Straw R, Fernando S, Evans A, Lacey T, Dearlove A, Greystrong J, Walker J, Watson P, Weston P, Kelly M, Taylor D, Gibson K, Mundy C, Bourgade F, Poirier C, Simon D, Brunialti AL, Montagutelli X, Gu'enet JL, Haynes A, Brown SD,

Link to Pubmed [PMID] – 9582196

Genome Res. 1998 May; 8(5): 531-42

The European Collaborative Interspecific Backcross (EUCIB) resource was constructed for the purposes of high-resolution genetic mapping of the mouse genome (). The large Mus spretus/C57BL/6 backcross of 982 progeny has a genetic resolution of 0.3 cM at the 95% confidence level ( approximately 500 kb in the mouse genome). We have used the EUCIB mapping resource to develop a genome-wide high-resolution genetic map incorporating 3368 microsatellites. The microsatellites are distributed among 2302 genetically separated bins with 1.46 markers per bin on average. Average bin separation is 0.61 cM. This high-resolution genetic map will aid the construction of a robust physical map of the mouse genome.