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Guides
  • 2022
    von Joest M, Chen C, Douché T, Chantrel J, Chiche A, Gianetto QG, Matondo M, Li H, , Amphiregulin mediates non-cell-autonomous effect of senescence on reprogramming., Cell Rep 2022 Jul; 40(2): 111074.
  • 2019
    Cazin C, von Joest M, Li H, Detecting Cellular Senescence in Reprogramming, Methods Mol. Biol. 2019;1896:1-10.
  • 2017
    Cazin C, Chiche A, Li H, Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle, J Vis Exp 2017 10;(128).
  • 2017
    Horikawa I, Park KY, Isogaya K, Hiyoshi Y, Li H, Anami K, Robles AI, Mondal AM, Fujita K, Serrano M, Harris CC., Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells, Cell Death Differ. 2017 Jun;24(6):1017-1028.
  • 2016
    Chiche A, Le Roux I, von Joest M, Sakai H, Aguín SB, Cazin C, Salam R, Fiette L, Alegria O, Flamant P, Tajbakhsh S, Li H, Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle, Cell Stem Cell 2017 03;20(3):407-414.e4.
  • 2016
    von Joest M1, Búa Aguín S1, Li H2., Genomic stability during cellular reprogramming: Mission impossible? Mutat Res. 2016 Jun;788:12-6,, Mutat Res. 2016 Jun;788:12-6.
  • 2015
    Ruiz S1, Lopez-Contreras AJ1, Gabut M2,3, Marion RM4, Gutierrez-Martinez P1, Bua S5, Ramirez O6, Olalde I6, Rodrigo-Perez S1, Li H5, Marques-Bonet T6,7, Serrano M8, Blasco MA4, Batada NN2,3, Fernandez-Capetillo O1., Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells, Nat Commun. 2015 Aug 21;6:8036.
  • 2014
    Choi YJ, Li H, Son MY, Wang XH, Fornsaglio JL, Sobol RW, Lee M, Vijg J, Imholz S, Dollé ME, van Steeg H, Reiling E, Hasty P, Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair, PLoS ONE 2014;9(1):e86358.
  • 2013
    Palla AR, Piazzolla D, Abad M, Li H, Dominguez O, Schonthaler HB, Wagner EF, Serrano M, Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer, Oncogene 2014 May;33(19):2513-9.
  • 2013
    Li H, Marple T, Hasty P, Ku80-deleted cells are defective at base excision repair, Mutat. Res. 2013 May-Jun;745-746:16-25.
  • 2012
    Li H, Collado M, Villasante A, Matheu A, Lynch CJ, Cañamero M, Rizzoti K, Carneiro C, Martínez G, Vidal A, Lovell-Badge R, Serrano M, p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation, Cell Stem Cell 2012 Dec;11(6):845-52.
  • 2011
    Menendez S, Camus S, Herreria A, Paramonov I, Morera LB, Collado M, Pekarik V, Maceda I, Edel M, Consiglio A, Sanchez A, Li H, Serrano M, Belmonte JC, Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency, Aging Cell 2012 Feb;11(1):41-50.
  • 2011
    Dumitrache LC, Hu L, Son MY, Li H, Wesevich A, Scully R, Stark J, Hasty P, Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair, Genetics 2011 Aug;188(4):787-97.
  • 2011
    Villasante A, Piazzolla D, Li H, Gomez-Lopez G, Djabali M, Serrano M, Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells, Cell Cycle 2011 May;10(9):1488-98.
  • 2010
    Lynch CJ, Shah ZH, Allison SJ, Ahmed SU, Ford J, Warnock LJ, Li H, Serrano M, Milner J, SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53, PLoS ONE 2010;5(10):e13502.
  • 2009
    Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, Fernandez-Capetillo O, Serrano M, Blasco MA, A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity, Nature 2009 Aug;460(7259):1149-53.
  • 2009
    Li H, Collado M, Villasante A, Strati K, Ortega S, Cañamero M, Blasco MA, Serrano M, The Ink4/Arf locus is a barrier for iPS cell reprogramming, Nature 2009 Aug;460(7259):1136-9.
  • 2009
    Li H, Choi YJ, Hanes MA, Marple T, Vogel H, Hasty P, Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells, Oncogene 2009 Apr;28(16):1875-8.
  • 2009
    Marion RM, Strati K, Li H, Tejera A, Schoeftner S, Ortega S, Serrano M, Blasco MA, Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells, Cell Stem Cell 2009 Feb;4(2):141-54.
  • 2008
    Li H, Mitchell JR, Hasty P, DNA double-strand breaks: a potential causative factor for mammalian aging?, Mech. Ageing Dev. 2008 Jul-Aug;129(7-8):416-24.
  • 2007
    Li H, Vogel H, Holcomb VB, Gu Y, Hasty P, Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer, Mol. Cell. Biol. 2007 Dec;27(23):8205-14.
  • 2005
    Yaneva M, Li H, Marple T, Hasty P, Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor, Nucleic Acids Res. 2005;33(16):5320-30.
  • 2004
    Marple T, Li H, Hasty P, A genotoxic screen: rapid analysis of cellular dose-response to a wide range of agents that either damage DNA or alter genome maintenance pathways, Mutat. Res. 2004 Oct;554(1-2):253-66.
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