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© Shalin E. Abraham, Michael Häusser, Christoph Schmidt-Hieber, University College London
The dentate gyrus is one of the few mammalian brain regions where new neurons are generated throughout life. The image was taken with a confocal microscope from a parasagittal slice of the mouse hippocampus. Cells were labelled with fluorescent markers: Newly generated neurons are red (doublecortin), mature neurons are green (NeuN), and nuclei are blue (DAPI)

How do we form and use distinct memories of resembling events? Scientists at the Institut Pasteur (Paris) have combined imaging and behavioral recording techniques to measure the activity of neurons in the hippocampus of mice. According to their observations, the input region of the hippocampus detects small changes between familiar and novel environments, while the output region then weights this information to guide behavioral decisions. This finding illustrates how the brain keeps the delicate balance between creating new memories and recalling existing ones.

Find out more: Here