Vanessa joined the lab in 2013 as a molecular/cell biology technician. Together with Gantas Perez-Mockus, she is studying the role of the E3 ubiquitin ligase Neuralized in epithelial morphogenesis, looking more specifically at the molecular targets of Neuralized.
Cytoskeleton and Mechanobiology projects
Until now, the role of actin in cell migration has been extensively studied, but much less is known about the role of microtubules and Intermediate Filaments(IFs) (Dutour-Provenzano and Etienne-Manneville, 2021, 34033784; Etienne-Manneville, 2018, 30059630). […]
Cell Polarity projects
What are the central components of polarity pathways ? Are they affected during gliomagenesis? Using astrocyte directed migration as a model system, we have identified evolutionary conserved polarity signals that control cell polarity […]
Epithelia form sheets of interconnected cells that are polarized along an apical-basal axis and perform selective exchange and barrier functions. Epithelia are dynamic structures that undergo remodeling associated with cell shape changes and neighbor […]