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© Deriano Lab / Institut Pasteur
Chromosomes métaphasiques d’une cellule lymphoïde cancéreuse présentant une amplification des gènes Igh et c-myc
Scientific Fields
Diseases
Organisms
Applications
Technique

Projects

Project
Completed
6 Members

ERC-2012-StG LymphoOncoGenomics

Ludovic Deriano (PI)

Deciphering the Oncogenic Lesions and Pathways of B and T Cell Cancers
Project
Ongoing
4 Members

FROM PHYSIOLOGICAL DNA REARRANGEMENTS TO LYMPHOID CANCERS

Ludovic Deriano (PI)

  B and T cell lymphoid cancers are among the most common human malignancies. Many factors, endogenous and exogenous, are implicated in the etiology of these disorders, but key oncogenic lesions often arise through […]
Project
Ongoing
5 Members

MECHANISMS OF DNA RECOMBINATION

Ludovic Deriano (PI)

  DNA double-strand breaks (DSBs), although common, are extremely dangerous (Deriano and Roth, Annual Review of Genetics, 2013). Unlike most other DNA lesions, DSBs directly threaten genomic integrity by disrupting the physical continuity of […]

Publications

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