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© Research

About

Glenda Comai is a CNRS permanent researcher at the Stem Cells and Development Unit. Her current research bridges the developmental biology and stem cells fields with focus on craniofacial muscles. Using 3D-imaging, mouse genetics and single cell/single nuclear omics she seeks to understand how heterogeneity at the level of stem cells and myofibres is established  and how this impacts on muscular genetic disorders. She has a long term interest in the mechanisms underlying tissue patterning during development.

Projects

Project
Completed
3 Members

AFM-Trampolin: Cellular and genetic basis for robustness of cranial myogenic populations (ENCRYPT)

Glenda Comai (PI)

Gene regulatory networks that act upstream of skeletal muscle fate determinants are distinct in different anatomical locations. Despite recent efforts, a clear understanding of the cascade of events underlying the emergence and maintenance of […]
Project
Ongoing
7 Members

ANR-JCJC: Mechanisms defining functional heterogeneity of anatomically distinct myogenic populations (MUSE)

Glenda Comai (PI)

The project at a glance: An unexpected finding was the discovery that muscle stem cells in different anatomical locations are programmed with distinct upstream regulators prior to acquiring myogenic identity. This intriguing observation is […]

CV

Current Position
  • 2016-Present: Permanent Researcher (CRCN CNRS) at Prof. Shahragim Tajbakhsh Lab. Department of Developmental and Stem Cell Biology, CNRS UMR 3738, Institut Pasteur, Paris. France.
  • 2019-Present: Member of the Advisory Board of the French Society of Developmental Biology (SFBD)
Awards
  • 2024-2026: AFM PRC Grant
  • 2021-2024: ANR JCJC Grant
  • 2020-2021: AFM Trampolin Grant
Research Experience
  • 2012-2016: Postdoctoral position at Prof. Shahragim Tajbakhsh Lab. Department of Developmental and Stem Cell Biology, CNRS UMR 3738, Institut Pasteur, Paris. France.
  • 2011: Postdoctoral position at Dr. Andreas Schedl Lab. INSERM U1091, Institute of Biology Valrose (iBV), University of Nice Sophia-Antipolis, Nice. France.
  • 2006-2010: Doctoral Researcher at Dr. Andreas Schedl Lab. INSERM U1091, Institute of Biology Valrose (iBV), University of Nice Sophia-Antipolis, Nice. France.
  • 2005: Graduate Student at Dr. Mario O. Aguilar Lab. Institute of Biochemistry and Molecular Biology (IBBM), La Plata National University. Argentina.
Education
  • 2024: HDR (Habilitation à diriger des Recherches), Université Paris Saclay, France.
  • 2010: Ph.D in Life Sciences, University of Nice Sophia-Antipolis, Nice. France. International Marie Curie PhD Program in Developmental and Cellular Decisions (InterDeC)
  • 2005: Chemist and Biochemist Diploma, La Plata National University, Faculty of Exact Sciences. Argentina.

Publications

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