My current research bridges the developmental biology and stem cells fields. I seek to understand how adult stem cell heterogeneity is established and how this impacts on muscular genetic disorders. I have a long term interest in the mechanisms underlying tissue patterning during development.
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Publications
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2021Dynamics of myogenic differentiation using a novel Myogenin knock-in reporter mouse., Skelet Muscle 2021 Feb; 11(1): 5.
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2020Local retinoic acid signaling directs emergence of the extraocular muscle functional unit., PLoS Biol 2020 Nov; 18(11): e3000902.
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2020Transcriptome and epigenome diversity and plasticity of muscle stem cells following transplantation., PLoS Genet 2020 Oct; 16(10): e1009022.
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2020Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation., Elife 2020 02; 9(): .
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2019An interactive and intuitive visualisation method for X-ray computed tomography data of biological samples in 3D Portable Document Format, Scientitific Report 9 (1): 14896.
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2019Muscle-selective RUNX3 dependence of sensorimotor circuit development, Development. 2019 Oct 15; 146(20): dev181750..
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2019A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle., Elife 2019 09; 8(): .
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2019A cell fitness selection model for neuronal survival during development., Nat Commun 2019 09; 10(1): 4137.
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2018Genetic and Molecular Insights Into Genotype-Phenotype Relationships in Osteopathia Striata With Cranial Sclerosis (OSCS) Through the Analysis of Novel Mouse Wtx Mutant Alleles., J Bone Miner Res 2018 05; 33(5): 875-887.
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2015A Cranial Mesoderm Origin for Esophagus Striated Muscles., Dev Cell. 2015 Sep 28;34(6):694-704.
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