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  • Director of Center
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© Research
Event

Regulation of IL-23R Expression in Human CD4+ T Cells and the Impact of IL-23 Blockade on Immune Responses in Vivo

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
20
Sep 2024
Time
14:00:00
Institut Pasteur, Rue du Docteur Roux, Paris, France
Address
Building: 67 Room: 45
Location
2024-09-20 14:00:00 2024-09-20 17:00:00 Europe/Paris Regulation of IL-23R Expression in Human CD4+ T Cells and the Impact of IL-23 Blockade on Immune Responses in Vivo This thesis explores the role of Interleukin 23 (IL-23) and its specific receptor (IL-23R) in chronic inflammatory diseases. The research uncovers the regulatory mechanisms of IL-23R expression, the impact of IL-23 in psoriasis, and […] Institut Pasteur, Rue du Docteur Roux, Paris, France Lars Rogge lars.rogge@pasteur.fr

About

This thesis explores the role of Interleukin 23 (IL-23) and its specific receptor (IL-23R) in chronic inflammatory diseases. The research uncovers the regulatory mechanisms of IL-23R expression, the impact of IL-23 in psoriasis, and highlights the complex transcriptional network involved. Findings reveal IL-21’s role in Th17 differentiation, the effects of IL-23 blockade in psoriasis, and the nuanced responses of immune cells to treatment, advancing our understanding of IL-23’s functions in human inflammatory diseases

Location

Building: 67
Room: 45
Address: Institut Pasteur, Rue du Docteur Roux, Paris, France