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THE APOPTOTIC FACTOR APAF1 INSIDE CELLS DURING CELL DEATH

© Institut Pasteur/Marco Gualtieri & Pauline Spéder

Event

DSCB Seminar: Dr. Aissam Ikmi, EMBL Heidelberg, Germany – “Design principles of cnidarian shapes”

Department of: Developmental and Stem Cell Biology

Member: Thibaut Brunet

Scientific Fields

Diseases

Organisms

Applications

Technique

Date

23

Jan 2026

Time

11:00:00

25 Rue du Docteur Roux, Paris, France

Address

Building: Monod Room: Amphi Ullmann

Location

2026-01-23 11:00:00 2026-01-23 12:00:00 Europe/Paris DSCB Seminar: Dr. Aissam Ikmi, EMBL Heidelberg, Germany – “Design principles of cnidarian shapes” Abstract: How do animals build, modify, and restore their shape? Shape is an organism-scale property that emerges from distributed molecular and biophysical processes coordinated across time and space, making causality inherently cross-scale. In this […] 25 Rue du Docteur Roux, Paris, France Thibaut Brunet thibaut.brunet@pasteur.fr

About

Abstract:

How do animals build, modify, and restore their shape? Shape is an organism-scale property that emerges from distributed molecular and biophysical processes coordinated across time and space, making causality inherently cross-scale. In this talk, I will discuss how morphological identity is achieved and re-established through the integration of biomechanics, behavior, and metabolism. Using cnidarians, whose relatively simple body architecture makes cross-scale causality experimentally tractable, we combine cross-species comparative analysis, genetics, quantitative imaging, and theory to identify the organizing principles of shape control. We show that cnidarian morphogenesis is governed by a small set of conserved mesoscale mechanical modules that generate evolutionary diversity, are dynamically regulated by physiology during life-cycle transitions, and are rescaled during regeneration to restore form from variable initial conditions.

Hosted by Thibaut Brunet

thibaut.brunet@pasteur.fr

Location

Building: Monod
Room: Amphi Ullmann
Address: 25 Rue du Docteur Roux, Paris, France

Published on: 15 Jan 2026

(function($) { /* * render_map * * This function will render a Google Map onto the selected jQuery element * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param $el (jQuery element) * @return n/a */ function render_map( $el ) { var MY_MAPTYPE_ID = 'custom_style'; var featureOpts = [{"stylers":[{"hue":"#0088ff"}]}]; var styledMapOptions = { name: 'Custom Style' }; var customMapType = new google.maps.StyledMapType(featureOpts, styledMapOptions); // var var $markers = $el.find('.marker'); // vars var args = { zoom : 16, scrollwheel : false, center : new google.maps.LatLng(0, 0), mapTypeId : google.maps.MapTypeId.ROADMAP, mapTypeId : MY_MAPTYPE_ID }; // create map var map = new google.maps.Map( $el[0], args); map.mapTypes.set(MY_MAPTYPE_ID, customMapType); // add a markers reference map.markers = []; // add markers $markers.each(function(){ add_marker( $(this), map ); }); // center map center_map( map ); } /* * add_marker * * This function will add a marker to the selected Google Map * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param $marker (jQuery element) * @param map (Google Map object) * @return n/a */ function add_marker( $marker, map ) { // var var latlng = new google.maps.LatLng( $marker.attr('data-lat'), $marker.attr('data-lng') ); //var image = 'https://research.pasteur.fr/wp-content/themes/biologyx2/images/logomap.png'; var myIcon = new google.maps.MarkerImage('https://research.pasteur.fr/wp-content/themes/biologyx2/images/map-pin.png', null, null, null, new google.maps.Size(32,32)); // create marker var marker = new google.maps.Marker({ position : latlng, map : map, icon : myIcon }); // add to array map.markers.push( marker ); // if marker contains HTML, add it to an infoWindow if( $marker.html() ) { // create info window var infowindow = new google.maps.InfoWindow({ content : $marker.html() }); // show info window when marker is clicked google.maps.event.addListener(marker, 'click', function() { infowindow.open( map, marker ); }); } } /* * center_map * * This function will center the map, showing all markers attached to this map * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param map (Google Map object) * @return n/a */ function center_map( map ) { // vars var bounds = new google.maps.LatLngBounds(); // loop through all markers and create bounds $.each( map.markers, function( i, marker ){ var latlng = new google.maps.LatLng( marker.position.lat(), marker.position.lng() ); bounds.extend( latlng ); }); // only 1 marker? if( map.markers.length == 1 ) { // set center of map map.setCenter( bounds.getCenter() ); map.setZoom( 15 ); } else { // fit to bounds map.fitBounds( bounds ); } } /* * document ready * * This function will render each map when the document is ready (page has loaded) * * @type function * @date 8/11/2013 * @since 5.0.0 * * @param n/a * @return n/a */ $(document).ready(function(){ $('.acf-map').each(function(){ render_map( $(this) ); }); }); })(jQuery);