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© Research
Event

DPT Parasites and Insects Vectors Seminar – David PEREZ-MORGA ” Human African Trypanosomiasis evolution and cell death in Trypanosoma brucei brucei – Chapter III”

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
20
Apr 2023
Time
12:00:00
Institut Pasteur, Rue du Docteur Roux, Paris, France
Address
Building: Lwoff Room: Retrovirus
Location
2023-04-20 12:00:00 2023-04-20 13:00:00 Europe/Paris DPT Parasites and Insects Vectors Seminar – David PEREZ-MORGA ” Human African Trypanosomiasis evolution and cell death in Trypanosoma brucei brucei – Chapter III” Séminaire du Département des Parasites et Insectes Vecteurs David PEREZ-MORGA Université Libre de Bruxelles “ Human African Trypanosomiasis evolution and cell death in Trypanosoma brucei brucei – Chapter III”  Jeudi 20 avril 2023, 12h00 […] Institut Pasteur, Rue du Docteur Roux, Paris, France Philippe Bastin philippe.bastin@pasteur.fr

About

Séminaire du Département des Parasites et Insectes Vecteurs

David PEREZ-MORGA
Université Libre de Bruxelles

Human African Trypanosomiasis evolution and cell death in Trypanosoma brucei brucei – Chapter III

 Jeudi 20 avril 2023, 12h00
Salle Rétrovirus – RDC Bâtiment Lwoff

Contact : philippe.bastin@pasteur.fr

Humans can survive bloodstream infection by African trypanosomes, such as Trypanosoma brucei brucei, owing to the trypanosome-killing activity of serum ApoL1. The two trypanosome subspecies that are responsible for human African trypanosomiasis, T. b. rhodesiense and T. b. gambiense, can evade this defence by expressing distinct resistance proteins. I will present the history and our latest findings on these resistance mechanisms and on the ApoL1-mediated cell death of T. b. brucei.

Your website: https://parasmol.ulb.be

Location

Building: Lwoff
Room: Retrovirus
Address: Institut Pasteur, Rue du Docteur Roux, Paris, France