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© Research
Event

Department of Parasites and Insect Vectors Seminar : Professor Gernot Längst “Chromatin Structure and Dynamics of Plasmodium falciparum”

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
11
Dec 2025
Time
12:00:00
Institut Pasteur, Rue du Docteur Roux, Paris, France
Address
Building: Lwoff Room: Retrovirus
Location
2025-12-11 12:00:00 2025-12-11 14:00:00 Europe/Paris Department of Parasites and Insect Vectors Seminar : Professor Gernot Längst “Chromatin Structure and Dynamics of Plasmodium falciparum” Abstact : The highly complex life cycle of the human malaria parasite, Plasmodium falciparum, relies on an orchestrated and tightly regulated gene expression programme. The access of regulatory factors to DNA is controlled by its packaging […] Institut Pasteur, Rue du Docteur Roux, Paris, France Gérald Spaeth gerald.spaeth@pasteur.fr

About

Abstact : The highly complex life cycle of the human malaria parasite, Plasmodium falciparum, relies on an orchestrated and tightly regulated gene expression programme. The access of regulatory factors to DNA is controlled by its packaging into nucleosomes, which limits DNA accessibility by binding to histone proteins. We are investigating the molecular mechanisms that determine DNA accessibility for regulatory factors, focusing on the role of chromatin remodelling complexes that are key regulators of gene expression. The talk will present new high-resolution insights into the parasite’s chromatin structure and the function of the essential chromatin remodelling enzyme PfSnf2L.

Website: www.laengstlab.com

Location

Building: Lwoff
Room: Retrovirus
Address: Institut Pasteur, Rue du Docteur Roux, Paris, France