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© Research
Event

Department of Neuroscience “Investigating the transcriptional changes at the basis of memory formation in the hippocampus”, by Baptiste N. JAEGER

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
13
Jun 2018
Time
11:30:00
25 Rue du Dr Roux, 75015 Paris, France
Address
Building: LWOLFF Room: Retrovirus Room
Location
2018-06-13 11:30:00 2018-06-13 12:30:00 Europe/Paris Department of Neuroscience “Investigating the transcriptional changes at the basis of memory formation in the hippocampus”, by Baptiste N. JAEGER Neuronal circuits are constantly refined and remodeled in response to activity. Activity-induced plasticity is responsible for the brain’s ability to adjust to changing conditions, as in the sculpting of circuits during development, adaptation after […] 25 Rue du Dr Roux, 75015 Paris, France

About

Neuronal circuits are constantly refined and remodeled in response to activity. Activity-induced plasticity is responsible for the brain’s ability to adjust to changing conditions, as in the sculpting of circuits during development, adaptation after injury, or incorporating new learning. Here, we used flow cytometry and RNA sequencing from single hippocampal neurons following behavioral stimulation to identify the molecular signature induced by neuronal activation and its consequence on future reactivation. Our results provide novel insights into how long-term activity-induced transcriptional changes are important for selecting the components of the original activated network that are ultimately involved in the encoding and retrieval of memories.

Location

Building: LWOLFF
Room: Retrovirus Room
Address: 25 Rue du Dr Roux, 75015 Paris, France