Microscale thermophoresis allows to monitor a great variety of molecular interactions rapidly and with a very low sample consumption, by measuring optically the mobility of macromolecules in a microscopic temperature gradient generated in a capillary tube.
The Monolith LabelFree detects the intrinsic fluorescence of tryptophans in proteins and peptides.
The PFBMI has also an instrument that detects extrinsinc fluorophores emitting at blue and red wavelengths (Monolith LabelFree , Nanotemper).