Our group studies the relationship between chromatin composition, genome organization, and transcription in the most virulent human malaria parasite, Plasmodium falciparum. Each stage of this parasite’s complicated life cycle between the human host and insect vector is driven by a specific transcriptional program. We are interested in discovering and elucidating the factors that regulate these dynamic transcriptional changes in the hopes of disrupting biological processes that are important for the parasite’s survival.
