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© Research
Publication : Organic letters

Mucorolactone, a Macrolactone from Mucor sp. SNB-VECD13A, a Fungus Isolated from the Cuticle of a Vespidae Species

Member: Isabelle Dusfour
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Organic letters - 20 Jun 2018

Touré S, Barthélémy M, Sorres J, Genta-Jouve G, Dusfour I, Eparvier V, Stien D

Link to Pubmed [PMID] – 29923409

Org. Lett. 2018 07;20(13):3780-3783

The newly discovered macrolactone, mucorolactone, along with eight known compounds, was isolated from an ethyl acetate extract of the insect-borne fungus Mucor sp. All structures were elucidated using 1D and 2D NMR and MS spectroscopic experiments. Relative and absolute configurations of the original skeleton of mucorolactone was deduced from NOESY experiments, from the C NMR chemical shift calculation based on the DP4 probability method, and from the comparison of experimental and calculated electronic circular dichroism spectra.