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© Research
Publication : PloS one

Frugal Droplet Microfluidics Using Consumer Opto-Electronics

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in PloS one - 25 Aug 2016

Frot C, Taccoen N, Baroud CN

Link to Pubmed [PMID] – 27560139

PLoS ONE 2016;11(8):e0161490

The maker movement has shown how off-the-shelf devices can be combined to perform operations that, until recently, required expensive specialized equipment. Applying this philosophy to microfluidic devices can play a fundamental role in disseminating these technologies outside specialist labs and into industrial use. Here we show how nanoliter droplets can be manipulated using a commercial DVD writer, interfaced with an Arduino electronic controller. We couple the optical setup with a droplet generation and manipulation device based on the “confinement gradients” approach. This device uses regions of different depths to generate and transport the droplets, which further simplifies the operation and reduces the need for precise flow control. The use of robust consumer electronics, combined with open source hardware, leads to a great reduction in the price of the device, as well as its footprint, without reducing its performance compared with the laboratory setup.