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© Research
Publication : Journal of virology

Prophage substitution and prophage loss from superinfected Escherichia coli recA(P1) lysogens

Team: Archived: Hepacivirus and Innate Immunity
Member: Eliane Meurs
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of virology - 01 Aug 1979

Meurs E, D'Ari R

Link to Pubmed [PMID] – 384020

J. Virol. 1979 Aug;31(2):277-80

It is shown that the plasmid prophage P1 can be displaced by a superinfecting P1 phage in Escherichia coli recA(P1) lysogens. Six widely separated phage markers were used to distinguish between residual recombination and total substitution. It is further shown that superinfection of recA lysogens can lead to loss of both phage (curing). These two phenomena, previously reported in Rec+ strains, are thus independent of host recombination and may result from perturbations of some function involved in plasmid maintenance.