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© Michel-Robert Popoff
Clostridium difficile en microscopie à contraste de phase. On distingue des bactéries sporulées, non sporulées et d'autres en cours de lyse (destruction). Bactérie de l'environnement (sol, eau, foin, sable), elle est à l'origine d'infections nosocomiales survenant après un traitement antibiotique : Clostridium difficile prédomine alors que les autres bactéries de la flore intestinale ont été détruites. L'infection peut provoquer deux types de pathologies graves : les colites pseudo-membraneuses dont l'origine est quasiment due à 100 % à C. difficile et la diarrhée post-antibiothérapie due à C. difficile dans 30 % des cas de ces diarrhées.
Publication : BMC microbiology

Decrypting the H-NS-dependent regulatory cascade of acid stress resistance in Escherichia coli

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in BMC microbiology - 29 Oct 2010

Krin E, Danchin A, Soutourina O

Link to Pubmed [PMID] – 21034467

BMC Microbiol. 2010;10:273

H-NS regulates the acid stress resistance. The present study aimed to characterize the H-NS-dependent cascade governing the acid stress resistance pathways and to define the interplay between the different regulators.