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© Research
Publication : Fungal genetics and biology : FG & B

A novel dehydrin-like protein from Aspergillus fumigatus regulates freezing tolerance

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Fungal genetics and biology : FG & B - 28 Jan 2012

Wong Sak Hoi J, Beau R, Latgé JP

Link to Pubmed [PMID] – 22306917

Fungal Genet. Biol. 2012 Mar;49(3):210-6

We recently reported on DprA and DprB, dehydrin-like proteins involved in the protection against oxidative, osmotic and pH stress in Aspergillus fumigatus. A third dehydrin-like gene, DprC, was detected in the genome of the filamentous fungus and repressed during conidial germination. The deletion mutant was impaired in freezing tolerance. The DprC-mediated response was dependent on the SakA MAP kinase pathway, and accordingly, SakA phosphorylation was induced by cold shock. When fused to eGFP, the protein was associated with the vacuoles.