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© Research
Publication : AIDS (London, England)

Immunosuppression and GB virus C-RNA detection among HIV-infected patients in Cambodia

Team: Epidemiology of Emerging Diseases
Member: Arnaud Fontanet
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in AIDS (London, England) - 12 May 2006

Sall AA, Ségéral O, Reynes JM, Lay S, Ouk V, Hak CR, Keo CL, Lefait RR, Delfraissy JF, Fontanet A

Link to Pubmed [PMID] – 16691073

AIDS 2006 May;20(8):1199-201

In this survey, 213 patients in an antiretroviral treatment programme in Phnom Penh, Cambodia, were tested for GB virus C (GBV-C) RNA before treatment initiation. Most had advanced HIV infection, only 34 having CD4 cell counts > 200 cells/microl. GBV-C-RNA was detected in 35 patients. The proportion with positive GBV-C-RNA decreased dramatically with CD4 cell counts < 100 cells/microl. In multivariate analysis, low CD4 cell counts, tuberculosis, anaemia, and traditional medicine were independently and negatively associated with GBV-C-RNA detection.