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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.
Publication : Microbes and infection / Institut Pasteur

How bacterial pathogens colonize their hosts and invade deeper tissues

Team: Bacteria-Cell Interactions
Member: Pascale Cossart
Member: David Ribet
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Microbes and infection / Institut Pasteur - 29 Jan 2015

Ribet D, Cossart P

Link to Pubmed [PMID] – 25637951

Microbes Infect. 2015 Mar;17(3):173-83

Bacterial pathogens have evolved a wide range of strategies to colonize and invade human organs, despite the presence of multiple host defense mechanisms. In this review, we will describe how pathogenic bacteria can adhere and multiply at the surface of host cells, how some bacteria can enter and proliferate inside these cells, and finally how pathogens may cross epithelial or endothelial host barriers and get access to internal tissues, leading to severe diseases in humans.