Ligne de temps
Jack Christophe Cossec
Chercheur(euse) Permanent(e)
07 janv. 2026
26 sept. 2025
publication
Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip.
Lire plus19 juil. 2025
publication
SUMO operates from a unique long tandem repeat to keep innate immunity in check.
Lire plus01 juin 2025
publication
Transient pharmacological inhibition of SUMOylation during pregnancy induces craniofacial malformations in offspring mice.
Lire plus17 sept. 2023
publication
Generation of embryo-like structures from mouse embryonic stem cells treated with a chemical inhibitor of SUMOylation and cultured in microdroplets.
Lire plus26 mai 2023
news
New publication – Transient suppression of SUMOylation in embryonic stem cells generates embryo like structures
Lire plus15 avr. 2023
publication
Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures.
Lire plus06 oct. 2021
project
Integrating the activities of SUMO in gene expression, inflammation and cancer (ERC-2011-AdG SUMOSTRESS)
Lire plus06 oct. 2021
06 oct. 2020
publication
Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells.
Lire plus15 sept. 2020
publication
Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells.
Lire plus24 juin 2020
publication
Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome.
Lire plus18 juil. 2019
project
Deconstructing the role of SUMO on chromatin in cell identity and tissue repair (ERC-2018-AdG SUMiDENTITY)
Lire plus01 nov. 2018
publication
SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States.
Lire plus22 oct. 2018
publication
SUMO safeguards somatic and pluripotent cell identities by enforcing distinct chromatin states
Lire plus19 juil. 2018
14 déc. 2015
publication
Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing.
Lire plus07 juil. 2015
publication
Modifications of the endosomal compartment in peripheral blood mononuclear cells and fibroblasts from Alzheimer’s disease patients.
Lire plus26 juil. 2013
publication
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation.
Lire plus17 avr. 2012
publication
Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes.
Lire plus01 janv. 2012
publication
Homodimerization of amyloid precursor protein at the plasma membrane: a homoFRET study by time-resolved fluorescence anisotropy imaging.
Lire plus01 avr. 2011
publication
Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis.
Lire plus01 août 2010
publication
Clathrin-dependent APP endocytosis and Abeta secretion are highly sensitive to the level of plasma membrane cholesterol.
Lire plus01 août 2010
publication
Cholesterol changes in Alzheimer’s disease: methods of analysis and impact on the formation of enlarged endosomes.
Lire plus01 mars 2010
publication
Enrichment of cholesterol in microdissected Alzheimer’s disease senile plaques as assessed by mass spectrometry.
Lire plus20 janv. 2009
publication
Time-gated total internal reflection fluorescence microscopy with a supercontinuum excitation source.
Lire plus21 mai 2006
publication