Timeline
Jack Christophe Cossec
Permanent Researcher
07 Jan 2026
26 Sep 2025
publication
Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip.
Read more19 Jul 2025
publication
SUMO operates from a unique long tandem repeat to keep innate immunity in check.
Read more01 Jun 2025
publication
Transient pharmacological inhibition of SUMOylation during pregnancy induces craniofacial malformations in offspring mice.
Read more17 Sep 2023
publication
Generation of embryo-like structures from mouse embryonic stem cells treated with a chemical inhibitor of SUMOylation and cultured in microdroplets.
Read more26 May 2023
news
New publication – Transient suppression of SUMOylation in embryonic stem cells generates embryo like structures
Read more15 Apr 2023
publication
Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures.
Read more06 Oct 2021
project
Integrating the activities of SUMO in gene expression, inflammation and cancer (ERC-2011-AdG SUMOSTRESS)
Read more06 Oct 2021
06 Oct 2020
publication
Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells.
Read more15 Sep 2020
publication
Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells.
Read more24 Jun 2020
publication
Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome.
Read more18 Jul 2019
project
Deconstructing the role of SUMO on chromatin in cell identity and tissue repair (ERC-2018-AdG SUMiDENTITY)
Read more01 Nov 2018
publication
SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States.
Read more22 Oct 2018
publication
SUMO safeguards somatic and pluripotent cell identities by enforcing distinct chromatin states
Read more19 Jul 2018
14 Dec 2015
publication
Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing.
Read more07 Jul 2015
publication
Modifications of the endosomal compartment in peripheral blood mononuclear cells and fibroblasts from Alzheimer’s disease patients.
Read more26 Jul 2013
publication
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation.
Read more17 Apr 2012
publication
Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes.
Read more01 Jan 2012
publication
Homodimerization of amyloid precursor protein at the plasma membrane: a homoFRET study by time-resolved fluorescence anisotropy imaging.
Read more01 Apr 2011
publication
Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis.
Read more01 Aug 2010
publication
Clathrin-dependent APP endocytosis and Abeta secretion are highly sensitive to the level of plasma membrane cholesterol.
Read more01 Aug 2010
publication
Cholesterol changes in Alzheimer’s disease: methods of analysis and impact on the formation of enlarged endosomes.
Read more01 Mar 2010
publication
Enrichment of cholesterol in microdissected Alzheimer’s disease senile plaques as assessed by mass spectrometry.
Read more20 Jan 2009
publication
Time-gated total internal reflection fluorescence microscopy with a supercontinuum excitation source.
Read more21 May 2006
publication