Timeline

Liliana Mancio Silva
Head of Structure
26 Apr 2024
publication

Autonomous circadian rhythms in the human hepatocyte regulate hepatic drug metabolism and inflammatory responses.

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16 Jan 2024
event

DPT Parasites and Insects Vectors Seminar – Elena LEVASHINA : “Early stages of mosquito colonization by Plasmodium falciparum”

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25 Apr 2023
news

World Malaria Day 2023: 2 lab articles highlighted by Cell Press

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17 Feb 2023
publication

Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum.

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11 Feb 2023
news

Celebrating Women And Girls In Science Day

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31 Jan 2023
news

ERC Consolidator Grant awarded to study dormancy, relapse and sexual conversion in malaria parasites

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11 Jan 2023
news

New publication: Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum

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20 Dec 2022
event

Host-parasite metabolic interactions during malaria infection (HDR defense Liliana Mancio)

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29 Sep 2022
publication

Repurposing of Plasmodium falciparum var genes beyond the blood stage.

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07 Sep 2022
event

Symposium “Future in Parasitology 2022”

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01 Sep 2022
news

Paludisme : recréer le cycle sanguin du parasite in vivo pour mieux lutter contre la maladie

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25 Aug 2022
publication

Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes.

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15 Jul 2022
news

New publication in Nature Communications: Humanized mice for sustained P. vivax blood-stage infection and transmission

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15 Jul 2022
publication

Humanized mice for investigating sustained Plasmodium vivax blood-stage infections and transmission.

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13 Jul 2022
publication

A single-cell liver atlas of Plasmodium vivax infection.

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04 Jun 2022
news

New publication in Trends in Parasitology: Single cell views of the Plasmodium life cycle

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04 Jun 2022
publication

Single-cell views of the Plasmodium life cycle.

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01 Jun 2022
news

Our work featured @inserm

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19 Apr 2022
news

New publication in Cell Host Microbe: A single-cell liver atlas of Plasmodium vivax infection

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01 Oct 2021
publication

Linking microbiota composition with antimalarial antibody response.

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02 Jul 2021
project

Host parasite metabolic interactions

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07 Feb 2020
team

Plasmodium Infection and Transmission

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21 Jan 2020
publication

Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes.

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19 Dec 2019
publication

Targeting liver stage malaria with metformin.

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14 May 2019
publication

γδ-T cells promote IFN-γ-dependent Plasmodium pathogenesis upon liver-stage infection.

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01 May 2019
publication

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes.

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04 Apr 2019
publication

Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles.

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05 Mar 2019
publication

Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers.

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14 Mar 2018
publication

In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites.

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01 Jan 2018
publication

Engineered Livers for Infectious Diseases.

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01 Jan 2018
publication

Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes.

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13 Jul 2017
publication

Nutrient sensing modulates malaria parasite virulence.

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01 Feb 2017
publication

GLUT1-mediated glucose uptake plays a crucial role during Plasmodium hepatic infection.

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06 Sep 2016
publication

Host AMPK Is a Modulator of Plasmodium Liver Infection.

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07 Aug 2015
publication

One nanoprobe, two pathogens: gold nanoprobes multiplexing for point-of-care.

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01 Apr 2015
publication

A mediator for malaria stickiness in A versus O blood.

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01 Jan 2013
publication

Sir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparum.

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01 Jan 2013
publication

In situ fluorescence visualization of transcription sites and genomic Loci in blood stages of Plasmodium falciparum.

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01 Sep 2012
publication

Two long non-coding RNAs generated from subtelomeric regions accumulate in a novel perinuclear compartment in Plasmodium falciparum.

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01 Aug 2012
publication

B7-CD28 costimulatory signals control the survival and proliferation of murine and human γδ T cells via IL-2 production.

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01 Mar 2012
publication

A novel carbon monoxide-releasing molecule fully protects mice from severe malaria.

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24 Aug 2010
publication

Clustering of dispersed ribosomal DNA and its role in gene regulation and chromosome-end associations in malaria parasites.

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01 May 2009
publication

Plasmodium falciparum heterochromatin protein 1 binds to tri-methylated histone 3 lysine 9 and is linked to mutually exclusive expression of var genes.

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14 Apr 2009
publication

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum

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01 Mar 2009
publication

Differential sub-nuclear localisation of repressive and activating histone methyl modifications in P. falciparum.

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19 Feb 2009
publication

Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites.

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15 Jun 2008
publication

Differential association of Orc1 and Sir2 proteins to telomeric domains in Plasmodium falciparum.

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08 Apr 2005
publication

Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites.

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01 Jan 2005
publication

The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus.

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