publication [25809]

3-Halo-3-nitro-aza/thioflavanones: DNMT inhibitors with a two-site binding mode in the hDNMT3A catalytic pocket3-Halo-3-nitro-aza/thioflavanones: DNMT inhibitors with a two-site binding mode in the hDNMT3A catalytic pocket

BioOrg. Med Chem.

Serhouni A, Calzaferri F, Bessina Y, van der Lee A, Arimondo PB, Louet M, Winum JY, Lopez M.

Disruption of deoxyribonucleotide triphosphate biosynthesis leads to RAS proto-oncogene activation and perturbation of mitochondrial metabolism

Journal of Biological Chemistry

Rodolphe Suspène, Kyle A. Raymond, Pablo Guardado-Calvo, Julien Dairou, Frédéric Bonhomme, Christine Bonenfant, Serge Guyetant, Thierry Lecomte, Jean-Christophe Pagès, Jean-Pierre Vartanian

Fungal impacts on Earth’s ecosystems.

Nature

Case NT, Gurr SJ, Fisher MC, Blehert DS, Boone C, Casadevall A, Chowdhary A, Cuomo CA, Currie CR, Denning DW, Ene IV, Fritz-Laylin LK, Gerstein AC, Gow NAR, Gusa A, Iliev ID, James TY, Jin H, Kahmann R, Klein BS, Kronstad JW, Ost KS, Peay KG, Shapiro RS, Sheppard DC, Shlezinger N, Stajich JE, Stukenbrock EH, Taylor JW, Wright GD, Cowen LE, Heitman J, Segre JA

Insight on the heterocyte patterning and the proheterocyte division in the toxic cyanobacterium Kaarinaea lacus gen. nov., sp. nov., and its genomic potential for natural products.

Harmful algae

Saraf A, Blondet E, Boullié A, Criscuolo A, Gugger M

International Committee on Systematics of Prokaryotes Subcommittee on the taxonomy of Leptospiraceae: minutes of the closed meeting, 3 September 2024, Brussels, Belgium.

International journal of systematic and evolutionary microbiology

Stone NE, Picardeau M

Leptospirosis-Improving Healthcare Outcomes for a Neglected Tropical Disease.

Open forum infectious diseases

Muñoz-Zanzi C, Dreyfus A, Limothai U, Foley W, Srisawat N, Picardeau M, Haake DA

Neurodevelopmental outcomes of infants after in utero exposure to SARS-CoV-2 or mRNA-COVID-19 vaccine compared with unexposed infants: a COVI-PREG prospective cohort study.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Favre G, Bromley RL, Bluett-Duncan M, Maisonneuve E, Pomar L, Daire C, Radan AP, Raio L, Surbek D, Blume C, Kalimeris S, Madec Y, Schneider J, Bickle Graz M, Winterfeld U, Panchaud A, Baud D

Novel lineage of anelloviruses with large genomes identified in dolphins

Journal of Virology

De Koch MD, Krupovic M, Fielding R, Smith K, Schiavone K, Hall KR, Reid VS, Boyea D, Smith EL, Schmidlin K, Fontenele RS, Koonin EV, Martin DP, Kraberger S, Varsani A

Immune control of brain physiology.

Nature reviews. Immunology

Kovacs M, Dominguez-Belloso A, Ali-Moussa S, Deczkowska A

Antibody-secreting cell repertoires hold high-affinity anti-rocuronium specificities that can induce anaphylaxis in vivo.

The Journal of allergy and clinical immunology

Dejoux A, Zhu Q, Woolfe A, Godon O, Ellouze S, Mottet G, Castrillon C, Gillis C, Pecalvel C, Ganneau C, Iannascoli B, Lemoine F, Saul F, England P, Reber LL, Gouel-Chéron A, de Chaisemartin L, Haouz A, Millot GA, Bay S, Gérard A, Jönsson F, Chollet-Martin S, Bruhns P

Design, Synthesis and Evaluation of Pyrimidinobenzylamide and Pyrimidinothiophenamide Derivatives as Inhibitors of DOT1L and Related Epigenetic Targets DNMT3a, PRMT4 and other HMTs

RSC Medicinal Chemistry,

Castillo- Aguilera O., Depreux P., Halby L., Bailly C., Domínguez-Ramírez L., Gul S., Arimondo P.B

Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosis.

EBioMedicine

Papadopoulos S, Hardy D, Vernel-Pauillac F, Tichit M, Boneca IG, Werts C

Neural circuits underlying context-dependent competition between defensive actions in Drosophila larvae

Nature Communications

Maxime Lehman, Chloé Barré, Md Amit Hasan, Benjamin Flament, Sandra Autran, Neena Dhiman, Peter Soba, Jean-Baptiste Masson, Tihana Jovanic

Cyclin O controls entry into the cell-cycle variant required for multiciliated cell differentiation

Cell Reports

Michella Khoury Damaa, Jacques Serizay, Rémi Balagué, Amélie-Rose Boudjema, Marion Faucourt, Nathalie Delgehyr, Kim Jee Goh, Hao Lu, Ee Kim Tan, Cameron T James, Catherine Faucon, Rana Mitri, Diana Carolin Bracht, Colin D Bingle, Norris Ray Dunn, Sebastian J Arnold, Laure-Emmanuelle Zaragosi, Pascal Barbry, Romain Koszul, Heymut Omran, Gabriel Gil-Gómez, Estelle Escudier, Marie Legendre, Sudipto Roy, Nathalie Spassky, Alice Meunier

In vitro microbiota model recapitulates and predicts individualised sensitivity to dietary emulsifier.

Gut

Rytter H, Naimi S, Wu G, Lewis J, Duquesnoy M, Vigué L, Tenaillon O, Belda E, Vazquez-Gomez M, Touly N, Arnone D, Hao F, Ley RE, Clément K, Peyrin-Biroulet L, Patterson AD, Gewirtz AT, Chassaing B

A look back at the departmental Virology Days of the Institut Pasteur (Le Touquet, May 13-15, 2024).

Journal of molecular cell biology

González R, Koh C, Virlon B, Merkling SH, Vartanian JP